Calcium Channel
Ca2+ channels; Ca channels
Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels. Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further reduce blood pressure, relieve chest pain (angina) and control an irregular heartbeat.
Calcium Channel Isoform Specific Products
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Calcium Channel Inhibitors
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Calcium Channel Agonists
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Calcium Channel Antagonists
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Calcium Channel Activators
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Calcium Channel Modulators
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Calcium Channel Chemical
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Calcium Channel Inducers
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Calcium Channel Controls
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Calcium Channel Ligands
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Calcium Channel Related Products (1237)
Related Products (1237)
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Antibodies (29)
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Related Compound Screening Libraries (1)
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Calcium Channel Isoform Comparison
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(S)-Azelnidipine
0 ImagesCat. No.: HY-167168CAS No.: 722455-09-6(S)-Azelnidipine is a calcium channel (Calcium Channel) blocker and the S-isomer of Azelnidipine, with potential for use in cardiovascular disease research.
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BMS-188107
0 ImagesCat. No.: HY-120180CAS No.: 139232-80-7BMS-188107 is a calcium antagonist that exerts anti-ischemic effects. BMS-188107 improves postischemic contractile function and reduces lactate dehydrogenase release. BMS-188107 can be utilized in cardiovascular research.
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Flavoxate-d4 (hydrochloride)
0 ImagesCat. No.: HY-B0549ASCAS No.: 1189678-43-0Flavoxate-d4 hydrochloride (Rec-7-0040-d4) is the deuterium labeled Flavoxate hydrochloride. Flavoxate hydrochloride (Rec-7-0040; DW61) is an orally active L-type Ca2+ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba2+ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions.
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Monatepil
0 ImagesCat. No.: HY-106818CAS No.: 103377-41-9Synonyms: AJ-2615 free baseMonatepil (AJ-2615 free base) is a calcium antagonist with potent α1-adrenoceptor blocking activity. Monatepil inhibits vasopressin- or methacholine-induced ischemic electrocardiographic changes in a rat model of vasospastic angina and reduces the mean arterial pressure in anesthetized rats. Monatepil also enhances low-density lipoprotein (LDL) receptor activity in human skin fibroblasts. Monatepil can be used in research related to hypertension, atherosclerosis, hyperlipidemia and vasospastic angina.
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Calcium Channel antagonist 5
0 ImagesCat. No.: HY-W037193CAS No.: 21829-09-4Calcium Channel antagonist 5 (compound 32) is a calcium channel antagonist with a pIC50 of 5.50.
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CP-060
0 ImagesCat. No.: HY-U00354CAS No.: 180090-15-7
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Dopropidil
0 ImagesCat. No.: HY-U00151CAS No.: 79700-61-1Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models.
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Darodipine
0 ImagesCat. No.: HY-U00086CAS No.: 72803-02-2Synonyms: PY 108-068; PY-108068Darodipine (PY 108-068, PY-108068) is a potent calcium channel antagonist.
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AE0047 Hydrochloride
0 ImagesCat. No.: HY-U00284CAS No.: 116308-56-6AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease.
